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Glucose Meter Designs Using HT45F and BH66/67 Series

Author : Adrian March 13, 2026

 

Standalone LCD Glucose Meter

Component Summary

  Part Number VDD IO/ADC TIMER ROM/RAM/EEP CLOCK Interface Others Package  
  HT45F65 2.2V~5.5V 37/12-bit×8 3 8K/256/- 4/8/12MHz HIRC SPI/I2C, UART, SPIA LCD driver, OPA, DAC, Temp sensor, Audio DAC 48/64 LQFP  
  HT45F66 59/12-bit×8 4 16K/512/- 64/80 LQFP  
HT45F67 32K/512/-  
  BH66F2450 39/12-bit×4 4 8K/256/64 LED driver, OPA, DAC, MDU, OVP 48 LQFP  
  BH66F2470 39/12-bit×4 32K/512/64  
? BH67F2470 46/12-bit×4 32K/768/64 LCD/LED driver, OPA, DAC, MDU, OVP 64/80 LQFP  

 

 

HCT Glucose Meter (Hematocrit Measurement)

Design reference: No. WAS-199c

Component Summary

  Part Number VDD IO/ADC TIMER ROM/RAM/EEP CLOCK Interface Others Package        
? BH67F2485 2.2V~5.5V 44/24-bit×6 4 48KW/4KB/128B 4/8/12/16 MHz SPI/I2C, SPIA, UART MDU, OPA, DAC, IAP, LCD driver, Phase detect 64/80 LQFP        

Applications

Glucose meters, lactate meters, and other devices that use LCD displays.

Key integrated features: precise DAC, LCD drive, and operational amplifiers suitable for current sensing and voltage excitation.

Low power and low component count: integrated ADC, DAC, OPA, and display drivers reduce external components.

 

Technical Overview

Accurate glucose monitoring is essential for diabetes management. Holtek provides MCUs combining 12-bit ADC, precise DAC, operational amplifiers, and integrated LCD drivers that are applicable to glucose and lactate meters. These MCUs support precise excitation voltages and I/V conversion using operational amplifiers, ADCs for analog-to-digital conversion, and LCD display support for result presentation.

HCT measurement is implemented using electrochemical methods that measure DC current from blood and enzyme reactions, as well as AC impedance and phase angle. The BH67F2485-based design integrates phase-angle and electrochemical measurement analog front-end circuitry. Using a high-precision DC excitation voltage, current measurements estimate glucose concentration. AC impedance and phase measurements at different frequencies and excitation amplitudes enable HCT estimation, which is used to compensate glucose readings across the full HCT range. Phase measurement accuracy is about ±0.3° and impedance accuracy is about ±1%.

Technical files such as block diagrams, circuit schematics, PCB layouts, and bill of materials are provided with the reference designs.